Status:
NOT_YET_RECRUITING
Biological and Clinical Underpinnings of Postoperative Pain - Colorectal Surgery
Lead Sponsor:
University of Alabama at Birmingham
Collaborating Sponsors:
National Institute of General Medical Sciences (NIGMS)
Conditions:
Colorectal Surgery
Eligibility:
All Genders
18-89 years
Brief Summary
Persistent pain after colorectal surgery remains a significant clinical challenge that can delay recovery, reduce quality of life, and increase long-term healthcare burden. The goal of this study is t...
Detailed Description
The overarching goal of this study is to elucidate the biological, psychological, and clinical factors that are responsible for pain trajectories following colorectal surgery. Using a biopsychosocial ...
Eligibility Criteria
Inclusion
- Participants scheduled for colorectal cancer surgery ; 2) age between 18-65; 3) understanding of verbal and written English.
Exclusion
- 1\) concurrent medical conditions that could confound the interpretation of the data; 2) HIV positive diagnosis; 3) cardiovascular or pulmonary disease; 4) systemic rheumatoid disease; 5) uncontrolled hypertension (i.e. SBP/DBP of \> 150/95); 6) current illness accompanied by fever (body temperature \>38 °C); 7) any other chronic pain condition; 8) conditions resulting in altered nerve sensation; 9) hospitalization due to psychiatric illness within the last 6 months; 10) poorly controlled diabetes; 11) history of stroke; 12) history of seizures; 13) circulatory disorders such AS Raynauds' disease 14) history of drug or alcohol abuse.
Key Trial Info
Start Date :
February 1 2026
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 1 2030
Estimated Enrollment :
128 Patients enrolled
Trial Details
Trial ID
NCT07219160
Start Date
February 1 2026
End Date
August 1 2030
Last Update
October 21 2025
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