Status:

RECRUITING

Effects of a 5-Week Probiotic Supplementation Intervention on Markers of Delayed Onset Muscle Soreness

Lead Sponsor:

University of Minnesota

Conditions:

Exercise Induced Muscle Damage

Delayed Onset Muscle Soreness (DOMS)

Eligibility:

All Genders

18-30 years

Phase:

NA

Brief Summary

The purpose of this study is to evaluate how probiotic supplementation (PS) influences post-exercise recovery in healthy, physically active young adults. Researchers aim to determine if the Lactobacil...

Eligibility Criteria

Inclusion

  • complete a minimum of 150 minutes a week of at least moderate intensity exercise in either an endurance-based or resistance-based training style based on a self-reported physical activity over the past month
  • good general health with no injuries or health conditions that would affect physical activity
  • willing to abstain from consistent NSAID use and other probiotic supplements over the course of this study

Exclusion

  • known musculoskeletal injuries or physical limitations that could interfere with performing the designated physical activity required
  • underlying conditions that could place them at an increased risk during exercise such as cardiovascular, respiratory, or metabolic diseases
  • currently take a probiotic supplement, are prescribed and taking an antibiotic during the intervention, or report using NSAIDs or steroids within the recovery time window
  • report using an NSAID more than twice a week on a regular basis

Key Trial Info

Start Date :

January 14 2026

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 30 2026

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT07219498

Start Date

January 14 2026

End Date

April 30 2026

Last Update

December 23 2025

Active Locations (1)

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1

University of Minnesota

Minneapolis, Minnesota, United States, 55455