Status:
NOT_YET_RECRUITING
Comparison of Suzetrigine and Oxycodone for Postoperative Pain After Primary Total Knee Arthroplasty
Lead Sponsor:
University of Louisville
Conditions:
Osteoarthritis (OA) of the Knee
Eligibility:
All Genders
21-89 years
Phase:
PHASE4
Brief Summary
The purpose this study is determine whether postoperative oral dosage of suzetrigine is effective at controlling postoperative pain and reducing analgesic requirements following primary total knee art...
Detailed Description
The purpose of this prospective, randomized study is to compare the outcomes of two cohorts of patients undergoing primary total knee arthroplasty (TKA) and to determine whether postoperative administ...
Eligibility Criteria
Inclusion
- Patient age is 21-89 at time of surgery
- Patient is scheduled to undergo a unilateral primary TKA, secondary to osteoarthritis
- Patient agrees to participate as a study subject and signs the Informed Consent and Research Authorization document
- Patient is able to read and speak English.
Exclusion
- Patient is under the age of 21
- Patient's primary diagnosis is not osteoarthritis
- Patient is unable to read and speak English
- Contraindication or Hypersensitivity to suzetrigine
- Pregnant or nursing females
- Patient has taken opioids within the 90 days prior to enrollment
Key Trial Info
Start Date :
December 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 29 2026
Estimated Enrollment :
140 Patients enrolled
Trial Details
Trial ID
NCT07219888
Start Date
December 1 2025
End Date
May 29 2026
Last Update
October 28 2025
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