Status:
RECRUITING
Parent-Based Treatment for Adolescent Anxiety
Lead Sponsor:
Yale University
Collaborating Sponsors:
MQ: Transforming Mental Health
Conditions:
Anxiety Disorder of Adolescence
Eligibility:
All Genders
14-17 years
Phase:
NA
Brief Summary
This study aims to test the efficacy of a parent-only approach to treating anxiety disorders in adolescents: SPACE (Supportive Parenting for Anxious Childhood Emotions). The comparator is another pare...
Detailed Description
The primary objective is to examine if SPACE is more efficacious than PES in reducing adolescent anxiety symptoms. The secondary objective is to examine if SPACE produces greater change than PES in im...
Eligibility Criteria
Inclusion
- Meet criteria for a primary DSM-5 AD, including separation anxiety disorder, social anxiety disorder, generalized anxiety disorder, specific phobia, panic disorder, and agoraphobia (determined by the ADIS-C/P).
- Cease all other psychosocial treatment, upon consultation with the project staff and service provider.
- Not currently use any psychotropic medication, other than a stable dose (i.e., same dose for a minimum of 6 months prior to enrollment; no changes during course of the study) of a stimulant medication or selective serotonin reuptake inhibitor (SSRI).
- Have an eligible and willing participating parent (see parent exclusions below).
Exclusion
- Adolescent:
- Meet criteria for any DSM-5 disorder more impairing than the most impairing AD (determined by the ADIS-C/P).
- Have any of the following disorders: autism spectrum disorder; intellectual disability; neurocognitive disorders; bipolar disorder; schizophrenia and other psychotic disorders; and alcohol and substance use disorders (determined by the Health History Form and ADIS-C/P).
- Report a suicide attempt in the last 3 months, or current suicide intent and plans (determined by the ASQ).
- Be a victim of past or present undisclosed abuse requiring investigation or ongoing supervision by the Department of Social Services.
- Not have sufficient proficiency with the English language to complete assessments.
- Parents:
- Have any of the following: intellectual disability; neurocognitive disorders; untreated bipolar disorder; untreated schizophrenia and other psychotic disorders; and untreated alcohol and substance use disorders (determined by the Health History Form).
- Not be living with the adolescent at least 50% of the time for at least one year prior to enrollment.
- Not have sufficient proficiency with the English language to complete assessments and treatment.
Key Trial Info
Start Date :
November 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2028
Estimated Enrollment :
108 Patients enrolled
Trial Details
Trial ID
NCT07219992
Start Date
November 1 2025
End Date
November 1 2028
Last Update
November 21 2025
Active Locations (1)
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1
Yale Child Study Center
New Haven, Connecticut, United States, 06519