Status:
RECRUITING
Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation
Lead Sponsor:
University of California, San Francisco
Conditions:
Obstructive Sleep Apnea
Premature Ventricular Contraction (PVC)
Eligibility:
All Genders
21+ years
Phase:
NA
Brief Summary
Whereas the available evidence mostly supports chronic sleep disruption as a risk factor for incident AF, less is known about the near-term risk of a discrete atrial fibrillation (AF) episode followin...
Detailed Description
One hundred patients aged 21 years or older who have a hypoglossal nerve stimulation (HGNS) device implanted for obstructive sleep apnea, without a history of permanent AF, not on Class 1 or 3 antiarr...
Eligibility Criteria
Inclusion
- Are age 21 years or older
- Have a HGNS device implanted for obstructive sleep apnea and followed up at UCSF Health
- Are willing to abstain from using the upper airway stimulation device for no more than two consecutive days as instructed over the 14-day trial period
- Able and willing to provide written informed consent
Exclusion
- Currently pregnant or trying to get pregnant
- Are currently taking class 1 or 3 anti-arrhythmic medications
- Have a history of permanent AF or expected to have continuous AF throughout the study period
- Have congenital heart disease
- Ventricular pacing \>40%
- Are unable to read or sign to provide informed consent
Key Trial Info
Start Date :
October 31 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2027
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT07220525
Start Date
October 31 2025
End Date
June 1 2027
Last Update
October 24 2025
Active Locations (1)
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1
UCSF Medical Center at Parnassus
San Francisco, California, United States, 94143