Status:
NOT_YET_RECRUITING
Sodium vs Potassium Education to Improve Vascular Health
Lead Sponsor:
Florida State University
Collaborating Sponsors:
United States Department of Agriculture (USDA)
Conditions:
Healthy
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to determine if a self-selected high potassium diet is easier to achieve and more effective at improving vascular health than a low sodium diet in generally healthy ...
Detailed Description
High sodium diets are a major contributor to cardiovascular disease. Unfortunately, reducing sodium intake can be challenging. It is known that increasing potassium intake can improve cardiovascular d...
Eligibility Criteria
Inclusion
- Willing and able to attend in-person laboratory visits
- Usual sodium intake ≥3,000 mg/d for females and ≥4,000 mg/d for males
- Usual potassium intake ≤2,500 mg/d in females and ≤3,000 mg/d in males
Exclusion
- BMI ≥35 kg/m2
- Seated blood pressure ≥130/80 mmHg
- Current diagnosis or history of diabetes, renal disease, cancer, cardiovascular disease, or major cardiovascular event (e.g. heart attack or stroke)
- Current or recent use of a diuretic (within the past 6 months)
- Elevated blood lipids (LDL cholesterol ≥190 mg/dL)
- Elevated serum potassium level (\>5.1 mmol/L)
- Elevated BUN (\>22 mg/dL)
- Elevated creatinine (\>1.2 mg/dL)
- Low eGFR (\<90 mL/min/1.73 m²)
- Current or recent use of tobacco, nicotine, or illicit drugs
- Radical hysterectomy or oophorectomy (females)\*
- Pregnant or lactating
- Following a weight-loss diet, or intending to gain or lose weight during the study period
Key Trial Info
Start Date :
January 7 2026
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 30 2027
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT07221448
Start Date
January 7 2026
End Date
September 30 2027
Last Update
October 28 2025
Active Locations (1)
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1
Florida State University
Tallahassee, Florida, United States, 32304