Status:
NOT_YET_RECRUITING
Preoperative Opioid Tapering Before Spine Surgery
Lead Sponsor:
Thomas Jefferson University
Conditions:
Opioid Consumption, Postoperative
Pain After Surgery
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This is a pilot study in which patients taking opioids chronically who are scheduled for spine surgery at least 4 weeks in advance will be randomly assigned to one of two groups: opioid tapering with ...
Detailed Description
The perioperative period represents a particularly problematic time for opioid-dependent patients. Perioperative pain is often difficult to control, with opioid tolerance, opioid-induced hyperalgesia,...
Eligibility Criteria
Inclusion
- Inclusion:
- at least 18 years old
- scheduled for major spine surgery (i.e. at least 2 levels of fusion) with hospital admission of at least one night
- scheduled for spine surgery at least 4 weeks ahead of time
- takes between 40 and 120 oral morphine equivalents daily
- Exclusion:
- inability to use a computer or tablet for telemedicine encounters
- non-English-speaking
- positive Urine Drug Screen for any drugs other than opioids or THC
- inability to complete assessments
- positive screen on the Columbia Suicide Screening Assessment
Exclusion
Key Trial Info
Start Date :
December 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT07221786
Start Date
December 1 2025
End Date
December 1 2026
Last Update
October 28 2025
Active Locations (1)
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1
Thomas Jefferson University Hospital
Philadephia, Pennsylvania, United States, 19107