Status:
NOT_YET_RECRUITING
Comparing Numbing Techniques in Mohs Micrographic Surgery
Lead Sponsor:
Abramson Cancer Center at Penn Medicine
Conditions:
Skin Cancer Face
Skin Cancer Scalp
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study seeks to determine whether adjunct regional nerve blocks reduce pain and anxiety in adult patients undergoing Mohs micrographic surgery for face and scalp skin cancers. Participants will be...
Detailed Description
This study is a prospective, randomized, single-center clinical trial involving adult patients undergoing Mohs micrographic surgery for cutaneous malignancy on the face and scalp. Patients will be ran...
Eligibility Criteria
Inclusion
- Age ≥18 years.
- Scheduled to undergo MMS.
- Lesions on the face or scalp, defined as the region superior to the mandibular margin anteriorly, superior to the external occipital protuberance posteriorly, and superior to the mastoid processes laterally.
- Tumor diameter plus anticipated stage 1 MMS margin ≥2 cm in diameter OR any tumor on the lip, nose, or eyelid.
- Ability to complete patient reported outcome measures in English.
Exclusion
- Known allergy or contraindication to lidocaine or epinephrine.
- Chronic opioid use or pre existing pain disorders that may interfere with pain reporting.
- Presence of scar tissue at the anatomic site of local infiltration or nerve block that may alter anesthetic penetration.
- Concurrent multi site Mohs procedure.
- Signs of skin and soft tissue infection at the anatomic site of local infiltration or nerve block.
- Inability to understand or complete pain and satisfaction assessments.
- Pregnant or breastfeeding.
- Use of sedatives or anxiolytics prior to the procedure.
Key Trial Info
Start Date :
February 1 2026
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 31 2026
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT07222241
Start Date
February 1 2026
End Date
July 31 2026
Last Update
January 8 2026
Active Locations (1)
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1
Perelman Center for Advanced Medicine
Philadelphia, Pennsylvania, United States, 19104