Status:

RECRUITING

One vs. Two Stents for Gallbladder Disease

Lead Sponsor:

Mayo Clinic

Conditions:

Recurrent Cholecystitis

Cholecystitis

Eligibility:

All Genders

18-95 years

Phase:

NA

Brief Summary

This randomized trial will look at whether placing two cystic duct stents is more effective than one cystic duct stent in preventing recurrent gallbladder disease (cholecystitis, gallstone pancreatiti...

Eligibility Criteria

Inclusion

  • Males or non-pregnant females presenting with cholecystitis, biliary colic or gallstone pancreatitis.
  • Age 18-95.
  • Participants must be willing and able to provide informed consent
  • Referred for ERCP for management of 1) suspected choledocholithiasis 2) acute biliary pancreatitis and/or 3) acute cholangitis in whom cholecystectomy is expected to be delayed \> 30 days or are deemed to not be surgical candidates for cholecystectomy.

Exclusion

  • Inability to provide informed consent
  • History of surgically altered upper gastrointestinal anatomy (e.g. Roux-en-Y gastric bypass, Billroth I/II) precluding standard ERCP
  • History of primary sclerosing cholangitis
  • History of gallbladder cancer
  • History of cholecystectomy
  • Unsuccessful biliary cannulation during ERCP -

Key Trial Info

Start Date :

December 12 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 27 2028

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT07222527

Start Date

December 12 2025

End Date

May 27 2028

Last Update

December 16 2025

Active Locations (1)

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Mayo Clinic

Rochester, Minnesota, United States, 55905