Status:
ENROLLING_BY_INVITATION
Hyperangulated Versus Standard Geometry Laryngoscope Blade Trial
Lead Sponsor:
Vanderbilt University Medical Center
Conditions:
Acute Respiratory Failure
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The Hyperangulated versus Standard Geometry Laryngoscope Blade (ANGLE) Trial is a multi-center, non-blinded, parallel-group, randomized clinical trial evaluating the effect of use of a hyperangulated ...
Detailed Description
Clinicians frequently perform tracheal intubation of critically ill patients in the emergency department (ED) or intensive care unit (ICU). In 10-20% of emergency tracheal intubations, clinicians are ...
Eligibility Criteria
Inclusion
- Inclusion Criteria
- Patient is located in a participating unit.
- Planned procedure is orotracheal intubation using a laryngoscope.
- Planned operator is a clinician expected to routinely perform tracheal intubation in the participating unit.
- Exclusion Criteria:
- Patient is known to be less than 18 years old.
- Patient is known to be pregnant.
- Patient is known to be a prisoner.
- Immediate need for tracheal intubation precludes safe performance of study procedures.
- Operator has determined that use of a direct laryngoscope is required for the optimal care of the patient.
- Operator has determined that use of a hyperangulated video laryngoscope blade or a standard geometry video laryngoscope blade is required or contraindicated for the optimal care of the patient either because of factors related to the patient (e.g., patient's upper airway anatomy requires a specific blade type) or the operator (e.g., treating clinicians lack sufficient comfort with one of the blade types).
Exclusion
Key Trial Info
Start Date :
December 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2027
Estimated Enrollment :
2500 Patients enrolled
Trial Details
Trial ID
NCT07223762
Start Date
December 1 2025
End Date
May 1 2027
Last Update
December 8 2025
Active Locations (7)
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1
University of Colorado, Denver Anschutz Medical Campus
Denver, Colorado, United States, 80045
2
Denver Health Medical Center
Denver, Colorado, United States, 80204
3
Rush University Medical Center
Chicago, Illinois, United States, 60612
4
Duke University Medical Center
Durham, North Carolina, United States, 27710